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Careful inquiry should then be made regarding compliance, dose of medication administered, and method of administration prior to raising the dose of Levothyroxine sodium.

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Factors Influencing Peripheral Conversion of Thyroxine to Tri-Iodothyronine in Athyreotic Individuals during Levothyroxine Replacement.

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We excluded studies of perioperative (cardiac surgery) LT 3 therapy from this section, since most of these studies included patients being given dopamine, which is known to suppress TSH and can cause iatrogenic hypothyroidism ().

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Congenital TSH deficiency may rarely be an isolated problem (caused by mutations in the TSH β subunit gene), but most commonly it is associated with other pituitary hormone deficiencies, as part of congenital hypopituitarism.

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As a matter of fact, these preparations do not report their dosage strength in milligrams, but rather, in grains of thyroid.

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Perceived allergy or intolerance to levothyroxine can be managed by changing the dose or product, including consideration of gel capsules, and possibly by treating concomitant iron-deficiency anemia.

Preventive Services Task Force does not recommend routine screening for hypothyroidism in asymptomatic persons.

Early consideration of this diagnosis and prompt institution of treatment might improve the final outcome in these patients.

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This new therapeutic approach, swept up in the nascence of organotherapy, began reshaping the way clinicians understood obesity, creating a new bipartite paradigm: exogenous, in which the root cause of obesity was attributed to overeating (“superalimentation”) in the absence of sufficient activity, and endogenous, characterized by diminished thyroid or other internal gland secretion.

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This causes the pituitary gland to secrete increasing amounts of thyroid stimulating hormone (TSH or thyrotropin), which, as its name implies, stimulates the thyroid gland to produce more T4 and T3 hormones.

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